“Small Natural Robots”
We’re in an odd spot. For a very long time, our tradition has been assuming that nature is our property and our slave. An unruly and hostile slave — a slave to be tamed, dominated, and abused — so long as we will get away with it and be ok with ourselves as we dominate.
A part of that mindset is that human beings are considered by probably the most highly effective folks in society as their slaves, too. It’s possible you’ll be center class and even higher center class … they don’t care. Of their thoughts, you’re their toy, exist for them. And because it goes, regardless of the masters do to nature or to the animals, they do to the folks subsequent.
For instance, as increasingly folks moved to cities, we have been informed to undertake the behavior of essentially chipping, vaccinating, and neutering our pets. It’s all for their very own good, proper? Properly, it began with chipping pets however now … I digress.
This story is in regards to the micro organism. After they speak about programmable micro organism or “micro organism with programmable DNA,” I see it as twin risk, On the one hand, I can’t assist however take into consideration the truth that to our masters, human beings on the bottom aren’t any completely different than micro organism. Persons are a useful resource to them — and they don’t seem to be shy about their want to program organic life, together with human life. That a lot, we all know.
Secondly, we don’t know something in regards to the long-term security of the merchandise produced with genetically modified bugs. And at this time, genetically modified microbes are a significant and nonetheless rising medium for the economic manufacturing of chemical substances, meals, medicines, therapeutic proteins, and so forth. And allegedly, producers don’t even must label such merchandise as GMO.
Bioengineered Meals: An Interlude
“Bioengineered” is the newest time period for GMO. Here’s a quote from the web page on the U.S. Division of Agriculture web site that accommodates producer FAQs. I’m utilizing their phrases verbatim in order that we will get guidelines and definitions straight out of their mouth.
Q: What data are enough to confirm {that a} meals is sourced from a non-bioengineered crop?
• Quite a lot of data could also be enough to confirm a meals is sourced from a non-bioengineered crop. A non-exhaustive record consists of: natural certification, data that present a non-BE crop selection was used, and data that present a meals originated in an space the place that particular BE meals is just not produced.
Q: What’s the threshold for bioengineered substance, and the way is it measured?
• The brink is designed to acknowledge the realities of the availability chain and acknowledge that BE and non-BE meals and elements are sometimes grown, harvested, transported, and processed in shut proximity to 1 one other. Due to this actuality, even when a non-BE ingredient is used, there could also be a hint quantity of a BE substance that is still on shared gear.
• The brink exempts meals by which no ingredient deliberately accommodates a bioengineered substance and permits for the inadvertent or technically unavoidable presence of a BE substance, of as much as 5 p.c, in every ingredient.
Q: I’m a regulated entity that will qualify for the very small meals producers exemption. How do I calculate my whole income?
• The Commonplace at 7 CFR 66.5(b) exempts very small meals producers from the BE disclosure necessities. At 7 CFR 66.1, very small meals producers are outlined as any meals producer with annual receipts of lower than $2,500,000 USD.
This quantity consists of all meals and non-food receipts. Meals producer is outlined as an entity that manufactures, processes, or packs human meals and labels the meals or meals product for retail sale.
Q. What’s a validated refining course of?
• A validated refining course of is one which has been demonstrated to make modified genetic materials undetectable when adopted. Validation is confirmed by means of testing and thru upkeep of processing data.
• AMS has printed a steering on validation and to pick out a check technique. Each the steering paperwork and related FAQs might be discovered below detectability testing.
Q. As soon as I’ve validated {that a} refining course of makes modified genetic materials undetectable, do I must proceed to check that course of?
• No, as soon as a course of has been validated by means of testing and a regulated entity maintains data displaying the validated course of is adopted, the method doesn’t should be examined once more until important adjustments are made to that refining course of.
And one other quote:
Q. If a uncooked materials has processing aids that aren’t labeled within the ingredient record on our completed product, would that be topic to disclosure below the Commonplace? For instance, we use a vitamin D that has a corn oil provider. We label the vitamin D on our completed product, however not the corn oil. If we all know the vitamin D is just not a bioengineered meals, does the completed product want a BE disclosure due to the corn oil provider?
• The definition of bioengineered meals, at 7 CFR 66.1, excludes incidental components which are current in meals at an insignificant degree and that would not have any technical or useful impact within the meals, as described in 21 CFR 101.100(a)(3). Incidental components, when utilized in accordance with this definition, usually are not required to be included on the ingredient record.
If the corn oil you’re utilizing as a processing help is taken into account an incidental additive as outlined in 21 CFR 101.100(a)(3), then it doesn’t require a bioengineered meals disclosure.
Are you impressed with these labeling requirements? I’m not.
Precision Fermentation
Precision fermentation is a way by which microorganisms are genetically reprogrammed to supply particular, custom-made molecules that may function new meals elements, industrial chemical compounds, therapeutic proteins, vaccines, and so on. Though the long-term results of such merchandise are unknown, from the business standpoint, precision fermentation is taken into account useful as it’s doubtlessly cheaper and extra scalable than producing chemical compounds instantly from crops, and so on.
In keeping with Forbes, it’s a “new meals expertise that’s quickly getting into the mainstream. Merchandise equivalent to milk protein, animal fat, collagen, honey, lobster, egg whites and extra are receiving lots of of thousands and thousands of investor {dollars} … These merchandise are being marketed to a younger shopper base that wishes sustainable, climate-friendly meals that buck the system and promise a greater tomorrow.” Hmmm, however is it so?
“Precision fermentation expertise is a type of artificial biology … that usually requires using genetically engineered microorganisms, that are cultivated in brewery-style fermentation tanks. The little critters, normally yeast, algae or micro organism, are programmed by means of a spread of in-vitro nucleic acid methods equivalent to CRISPR, gene modifying or cloning.
They produce or excrete a selected sellable materials, normally edible fat or proteins which are biologically much like animal merchandise. These finish merchandise might be additional processed into elements or completed CPG gadgets.”
“The … new Nationwide Bioengineered Meals Disclosure Commonplace wouldn’t require these meals to be labeled as GMO as a result of they don’t comprise the genetically engineered organisms, they’re simply produced by them. Such merchandise would subsequently not qualify for Non GMO Challenge Verification. As a result of some could also be thought-about novel meals, it isn’t clear how they are going to be labeled or regulated in Europe.
And since they’re animal-free, they could be thought-about vegan, however will nonetheless must have the identical allergen labeling as their animal-based counterparts.”
What in regards to the cell tradition medium? Is it actually as impartial and insignificant as we’re led to consider?? Even Forbes has query. “Is the nutrient tub derived from corn or soy, usually genetically modified to resist excessive dosages of herbicides? Are there provide chains in place to supply such nutrient media at scale? […] How a lot waste materials is produced by such microorganisms relative to sellable product?
This consists of metabolic wastes, in addition to the leftover steep as soon as the spent microbes and consumable materials have been filtered out. How will such wastes be disposed of and who’s in the end answerable for it?”
Oh cease asking foolish questions, says the business. In keeping with Meals Navigator, in its 2020 report on precision fermentation in dairy, RethinkX predicted that the expertise would make protein manufacturing “5 occasions cheaper by 2030 and 10 occasions cheaper by 2035 than current animal proteins.”
The “promotional brochure” for the merchandise made with precision fermentation would have you ever consider that they’re pure and secure. Precision fermentation, nonetheless, is “nothing like its pure counterpart … It makes use of genetically engineered microorganisms, equivalent to yeast and micro organism, which are fermented in brewery-style tanks below high-tech, pharmaceutical grade sterile situations.
It is because these cultures are extremely prone to contamination which might smash all the batch … The long-term outcomes are fully unknown … However it’s all serving the underlying agenda, which is whole management and world domination … These faux, ultraprocessed meals give the globalists unprecedented energy and management over human well being, they usually’re utilizing stealthy advertising methods.”
“Pure Merchandise”
“Pure merchandise” can also be a proper time period to explain a selected kind of metabolite, the secondary metabolite. In keeping with this Harvard College article, some organisms, equivalent to crops, fungi and micro organism, are in a position to create a category of molecules known as secondary metabolites, or pure merchandise.
Researchers consider that they play no direct position within the organism’s regular development or replica as eradicating these molecules from the organism doesn’t lead to instant dying. Nonetheless, these organisms depend on pure merchandise designed for particular duties, equivalent to safety towards different organisms or interplay with their very own species.
“As a result of these molecules are made to impact different organisms in varied methods, they are often very helpful as therapeutics. For instance, they can be utilized to kill dangerous micro organism infecting people, and even have an impact instantly on human cells for varied therapeutic functions. In truth, most of our medicines are literally derived from or impressed by pure merchandise.”
“One vital use of pure merchandise is antibiotics. Ever for the reason that serendipitous discovery of penicillin in 1928, which was a pure product from fungi that would kill micro organism … Along with antibiotics, many bacterial pure merchandise produce other therapeutic makes use of.
For instance, rapamycin, also referred to as sirolimus, is made by the micro organism Streptomyces hygroscopicus, and is used clinically as an immunosuppressant, particularly throughout a kidney transplant. Bleomycin, a pure product discovered from Streptomyces verticillus, is a chemotherapy drug used within the remedy for a spread of cancers.”
Industrial Microbiology
Microorganisms play a major position in industrial manufacturing, and new processes involving microbes are being researched as we converse.
For instance, micro organism can doubtlessly “heal” concrete. Researchers on the College of Tub are investigating how some species of Bacillus micro organism might be used to make concrete that may “heal” itself.
As a skeptical peasant with no expertise in building, I’m enthusiastic about “therapeutic” concrete however I absolutely hope that they check this materials totally to make it possible for the spores they search to combine into the concrete don’t “leach” and make all the pieces round us some type of a GMO spore fest.
Scientific Information Is Restricted
Genetically modified microbes sound nice for the underside line — however do the scientists know in earnest how issues work, and what results in what? Are they positive? If we’re to consider this paper, they don’t seem to be.
“Regardless of mounting proof linking host-associated micro organism to regular growth and illness in animal fashions and correlative proof in people, the mechanisms by which particular bacterial features have an effect on mammalian or microbiome physiology (i.e., effector features) stay largely undefined [emphasis mine].
The central dogma of molecular biology, historically outlined because the switch of knowledge from DNA to RNA to protein, stops wanting the last word finish level of a lot of the data move in a organic system. In a major fraction of mobile processes, the top level of knowledge move is just not a protein however is, as a substitute, a small molecule.
That is very true for micro organism which rely closely on low-molecular-weight compounds (i.e., small molecules or pure merchandise) to work together with their environment. The systematic characterization of small molecules produced by human-associated micro organism will undoubtedly be key to deciphering the mechanistic particulars of the position the human microbiome performs in our well being and illness.”
Bacterial Biosensors
In keeping with a paper titled “Bacterial biosensors: The way forward for analyte detection,” micro organism include lots of sensors — and, per Caroline Ajo-Franklin, Ph.D., a professor of biosciences at Rice College whose artificial biology lab develops microbial biosensors, “these sensors do not simply sense, they [also] inform the micro organism to do one thing.”
The researchers need to “leverage these pure responses to have the micro organism inform us, as people, what they’re seeing [and] what they’re feeling.”
The final precept of a whole-cell microbial biosensor is to program a cell (usually by means of genetic engineering) to acknowledge and generate a measurable sign in response to a selected molecule. When producing biosensors, scientists “co-opt these responses [with a transducer] in order that as a substitute of getting cells that simply make [products like] efflux pumps, [researchers] engineer them to create a response [the scientists] can learn.”
“Relying on the biosensor and its supposed use, this response might be electrochemical or contain expression of fluorescent or luminescent reporter proteins. Complete-cell biosensors are sometimes engineered to work solely when their goal molecule is current. This skill to fine-tune specificity and sensitivity has made bacterial biosensors promising analytical instruments.”
Complete-cell biosensors can “present perception on nutrient ranges and natural compounds in soils, which might inform strategies for managing crop development. They’ll additionally sign the presence and ranges of probably problematic compounds.”
“Along with vitamins and poisonous compounds, bacterial biosensors might be designed to reply to … different micro organism. Microbes secrete all types of metabolites, a lot of which might function goal analytes. As an illustration, microbial biosensors that detect quorum sensing molecules secreted by bacterial pathogens can sign the presence of disease-causing microbes in water, or in human samples to assist diagnose infections.”
“Bacterial biosensors might present helpful intel into the well being of human sufferers. A current examine described a biosensor constituted of the environmental bacterium, Acinetobacter baylyi, that may detect DNA from most cancers cells in vitro and in a mouse mannequin. This examine supplies a foundation for the appliance of microbial biosensors in most cancers detection and analysis.
Scientists have additionally created ingestible biosensors that may detect bleeding or inflammatory biomarkers within the intestine to observe intestinal well being; the alerts from these inner microbial units might be transmitted to exterior units, like cellphones, thus illustrating how biosensors might be paired with current digital applied sciences to facilitate knowledge assortment and evaluation.”
My two cents? On the one hand, it’s great to have the ability to detect pollution round us (assuming it really works). It might be great however … however the issue is that as regular, the scientists haven’t any clue about what’ll occur in the long run. Will these so known as “small natural robots” assist with one factor and break ten different issues? And the way will we even clear up? Scientists don’t appear to care. Buyers chortle on the very thought. And who shall be caught with the invoice? Our our bodies. Us.
Graphene Oxide within the Mind: Yay
Talking of getting no clue, this 2023 paper titled, “Graphene Oxide Attenuates Toxicity of Amyloid-β Aggregates in Yeast by Selling Disassembly and Boosting Mobile Stress Response,” talks about utilizing graphene oxide to assist with Alzheimer’s illness.
What an amazing concept! The strategy relies on the power of GO nanoflakes to counter the aggregation of misfolded amyloid-β (Aβ) peptides within the mind. However what if these misfolded proteins are the mind’s response to an infection?
In spite of everything, the “infectious” idea of Alzheimer’s illness has been identified for some years, and an infection and ensuing irritation might be outstanding elements in creating AD. Then need? Are we simply going to wash the mind in GO nanoflakes till the individual drops useless? To not point out GO toxicity, conductivity, and the Web of Issues. Jeez.
“Alzheimer’s illness (AD) is probably the most prevalent neurodegenerative illness, with the aggregation of misfolded amyloid-β (Aβ) peptides within the mind being one among its histopathological hallmarks. Not too long ago, graphene oxide (GO) nanoflakes have attracted important consideration in biomedical areas as a consequence of their capability of suppressing Aβ aggregation in vitro.
The mechanism of this useful impact has not been totally understood in vivo. Herein, the impression of GO on intracellular Aβ42 aggregates and cytotoxicity is investigated utilizing yeast Saccharomyces cerevisiae because the mannequin organism. This examine finds that GO nanoflakes can successfully penetrate yeast cells and cut back Aβ42 toxicity.
Mixture of proteomics knowledge and follow-up experiments present that GO remedy alters mobile metabolism to will increase mobile resistance to misfolded protein stress and oxidative stress, and reduces quantities of intracellular Aβ42 oligomers. Moreover, GO remedy additionally reduces HTT103QP toxicity within the Huntington’s illness (HD) yeast mannequin.
The findings provide insights for rationally designing GO nanoflakes-based therapies for attenuating cytotoxicity of Aβ42, and doubtlessly of different misfolded proteins concerned in neurodegenerative pathology.”
Need for Management … and Us
It seems to be like lots of this artificial insanity is pushed by the need to manage. The need to manage performs an vital position in our tradition and in our medical paradigms. All in all, we live below the rule of loopy maniacs who search absolute management! It’s a really distorted, neurotic, joyless rule.
The loopy maniacs — the dominators, the power-seeking psychological kind — have been behind each massive atrocity, each not so nice reset for hundreds of years on finish, each main abuse. And they don’t seem to be letting go.
Sure, I consider that what’s driving the not so nice reset is want for management. That want has been driving our civilization for fairly some time. It is extremely logical that the individuals who wish to have management search to switch the pure world with an artificial world. In an artificial world, they’ll impose their guidelines. An artificial world, they’ll management — or no less than strive. So what can we do?
I consider that what we do is keep vigilant, educate ourselves, preserve issues in perspective, and demand on the legitimacy of our love of life. The aspiring masters need us to be afraid and unhappy. They need us to carry our head down and to be slaves. However we aren’t slaves! And if we do completely all the pieces from the place of affection — robust, assured, non-push-over love — we are going to show not simply with our phrases however with our actions that we aren’t slaves. As a result of slaves, we aren’t.
In regards to the Writer
To seek out extra of Tessa Lena’s work, make sure you take a look at her bio, Tessa Fights Robots.
